Non-linear dynamic processes and their correlation with indicators of microcirculation in patients with obliterating atherosclerosis of the lower extremities arteries according to laser doppler flowmetry

Objective : To study features of nonlinear dynamic and oscillatory processes in the skin microcirculatory flow patients with obliterating atherosclerosis lower extremities arteries (OALEA). Material methods. 56 male 15 practically healthy individuals were taken into study. Microcirculation on feet assessment spectral wavelet analysis blood fl ow uctuations was studied by laser Doppler flowmetry, device “LACK-M” (firm Lazma, Russia). Normalized amplitude parameters fluctuations frequency ranges hemocirculation tonus-forming factors analyzed: endothelial, neurogenic, myogenic. Myogenic microvascular tone capillary indices calculated. processes, following assessed: fractal dimension, entropy phase portrait analysis. Results . Spastic-atonic microcirculation disorders revealed OALEA. They characterized metarteriole constriction restriction flow, an increased myogenic dilated arterioles. Statistically significant shifts dynamics this case- particular, decrease (–10.6 %) dimensions (–9.3%) under energy deficit (–20.8 – can be interpreted as a complexity flowmetric signal better ordering regulatory mechanisms peripheral flow. Conclusion In extremities, obtained results indicate functional spastic-atonic nature leading to nutritive accompanied lack processes. These have also shown system chaos severity which indicates limitation connections control factors, simplification functioning bed and, consequence, compensatory adaptive potential.